Definition:
Collection of fluid in lung interstitial space and/or alveolar spaces. Characterised by extreme breathlessness.
Causes:
Heart failure.
Pathophysiology:
Pressure above 20mmHg causes fluid filtration from capillaries into interstitial space. Further accumulation of fluid disrupts intercellular membranes, leading to collection of fluid in alveolar spaces.
Signs and symptoms:
Acutely breathlessness, wheezing, anxiety and profuse sweating. Cough productive of frothy, blood-tinged sputum. Tachypnoeic with peripheral circulatory shutdown. Tachycardia, raised venous pressure and gallop rhythm. Crackles and wheezes are heard throughout the chest.
Investigations:
CXR - diffuse haziness, owing to alveolar fluid and lines of interstitial oedema. Can be unilateral, giving the appearance of a tumour that disappears on treatment.
Management:
Place in sitting position, high-concentration oxygen/ventilation. Intravenous diuretics, morphine, venous dilators, bronchodilators.
Prognosis:
Acute emergency.
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